Civatte bodies in oral lichen planus—distribution variety, diagnostic significance and histopathogenesis | Scientific Reports; noi Beţivan admite Discoid lupus

The dermal papillae between the elongated rete ridges are frequently dome shaped. Necrotic keratinocytes can be observed in the basal layer of the epidermis and at the dermal-epidermal junction. Eosinophilic remnants of anucleate apoptotic basal cells may also be found in the dermis and are referred to as “colloid or civatte bodies”.

Lichen planus may occur on mucosal surfaces such as the oral mucosa or genitalia. 2013-07-01 · Introduction. The presence of numerous civatte bodies (CBs) in biopsies is a characteristic finding in skin lesions of patients with various dermatoses, particularly lichen planus (LP) and discoid lupus erythematosus (DLE). In the absence of a clear diagnosis, their presence is suggestive of disorders characterized by interface dermatitis.

The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies), and obscuring of the dermo-epidermal Key Words: Apoptosis, civatte bodies, colloid bodies, oral lichen planus, oral lichenoid reaction. histological features of OLP are the subepithelial band. Apoptosis of basal layer keratinocytes results in 'Civatte bodies' (in lichen planus and Histologically the abnormal keratinocytes have increase/accumulation of so bezeichnet man sie als „Civatte bodies“, „cytoid bodies“ oder „Kolloid bodies“. New observations and correlations of clinical and histologic findings. 22 Jul 2015 and confirmed by the presence of typical Civatte bodies on histopathology and fibrin deposition on direct immunofluorescence.

A Civatte body (named after the French dermatologist Achille Civatte, 1877–1956) is a damaged basal keratinocyte that has undergone apoptosis, and consist largely of keratin intermediate filaments, and are almost invariably covered with immunoglobulins, mainly IgM. Civatte, Achille, French dermatologist, 1877-1956.

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Chapter 23, Female Reproductive System (pgs 773-790, Ovary and Uterine Tubes) Although emergence of keratin 17 (K17) and reciprocal loss of K13 are immunohistochemical hallmarks for oral mucosal malignancy, we report here findings of K17-positive (+) speckles, possibly equivalent to Civatte bodies, in benign oral lichen planus. Sixty-two biopsy samples from oral lichen planus cases were subjected to immunohistochemical examinations to analyze the distribution as well as Se hela listan på hindawi.com Shotgun Histology Ovary 2012-06-07 · Histology and cytology are two branches of biology that study the tissues of animals and plants and cells microscopically. CONTENTS. 1.

Civatte bodies were not confined to the basal layer. The findings suggest that cell-mediated regression may occur in common warts, similar to that described in plane warts. Warts treated with injections of bleomycin show confluent epidermal necrosis, single apoptotic keratinocytes, and diffuse neutrophil infiltration of the epidermis, with

[Article in German] Narwutsch M, Narwutsch M. In a histological and immunofluorescence microscopic study on 145 patients suffering from lichen planus the PUVA-effects on the keratin bodies are observed. How is poikiloderma of Civatte diagnosed?

Poikiloderma of Civatte is a benign skin condition that was first described in 1923 by Civatte, a French dermatologist.Also known as sun aging, this is a medical condition that appears as a direct result of the chronic exposure to the sun, affecting primarily the neck and chest area. CIVATTE BODIES AND APOPTOSIS CIVATTE BODIES AND APOPTOSIS WEEDON, DAVID 1974-09-01 00:00:00 SIR, The ultrastructure of Civatte bodies in lichen planus, as illustrated in the recent paper by ElLabban & Kramer (1974), is typical of 'apoptosis', the morphologically distinct type of cellular death described by Kerr, Wyllie & Currie (1972).
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Civatte bodies are highly Civatte bodies (CBs) are found in various characteristic skin lesions, and their presence is suggestive of disorders characterized by interface dermatitis. These bodies are generated by damaged basal keratinocytes through apoptotic cell death, consist largely of keratin intermediate filaments, and are almost Civatte bodies. • Schaumann bodies. (D) Blood dyscrasias: • Heinz bodies. • Howell–Jolly bodies.

Diseases→ discoid lupus erythematosus and lichen planus.
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Pathological and non-pathological bodies is the 'must have' reference website for the biological, medical and biomedical sciences. The site comprises more than 250 bodies, most of which are related to disease processes.

Dyskeratotic keratinocytes (so called Civatte bodies) are frequently seen at the basal layer. Civatte bodies are PAS positive. Eosinophils are uncommon in conventional cutaneous lichen planus. Lichen planus may occur on mucosal surfaces such as the oral mucosa or genitalia.

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Civatte bodies though are one of the key features in the four major histological changes in lichenoid dermatoses histopathologically they were found to be less correlated in ours as well in other similar studies (Hegde and Khadilkar, 2014). Caspary-Joseph spaces were seen in very few cases (2.5%) in our study.

Foreign body - a mass or entity that has been introduced from an external source.

The diagnosis of poikiloderma of Civatte is made clinically. A punch biopsy can show typical histology with hyperkeratosis, epidermal atrophy, pigmentary incontinence, telangiectasia, a variable superficial dermal lymphohistiocytic infiltrate, and solar elastosis.

Even after Achille Civatte discussed and beautifully illustrated them a 2010-11-30 · Buscaino bodies are thought to be caused by solubilization and subsequent precipitation (by fixation) of some myelin component (Ibrahim and Levine 1967). These structures are typically pale but may be slightly basophilic or gray in color, as well as metachromatic or periodic acid-Schiff (PAS)-positive (Vinters and Kleinschmidt-DeMasters 2008).

Poikiloderma of Civatte, also known as sun aging, is a condition caused by sun exposure. The skin changes as a result of chronic, long term exposure to the sun as well as normal aging. Chronically exposed children can acquire significant damage by age 15. These affects may also become apparent as early as age 20. erythrosis interfollicularis colli / poikiloderma van civatte ICD10 : L57.3 Erythrosis interfollicularis colli is een door blootstelling aan zonlicht veroorzaakt teleangiectatisch erytheem op de zijkant van de hals of op het coeur, waarbij de perifolliculaire huid gespaard blijft.Het ontstaat door solaire schade aan het bindweefsel, inclusief het steunweefsel rond capillairen. 1981, 135 (3), 219-229 - So-called Civatte bodies and dyskeratotic cells were investigated in some skin disorders by using indirect immunofluorescence techniques with anti-human keratin antibody. In the disorders with lichenoid tissue reaction such as lichen planus and DLE, Civatte bodies were observed in 20170405 111817Stained to reveal RNA-leaden Nissl bodies bodies (the rough ER of a neuron), negative-stained nucleus, nucleolus, axon hillock and initial seg 2017-04-28 · Poikiloderma of Civatte refers to erythema associated with a mottled pigmentation seen on the sides of the neck, more commonly in women.